Thermo Scientific Lab Vision p53 Ab-8, Mouse Monoclonal Antibody
Deliver accurate, reproducible results with the Thermo Scientific p53 Ab-8, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific MS738PABX
Deliver accurate, reproducible results with the Thermo Scientific p53 Ab-8, Mouse Monoclonal Antibody.p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Host Species: Mouse
Clone: DO-7 + BP53-12
Isotype: IgG2b + IgG2a
Species Reactivity: Human. Others not known.
Epitope: aa 37-45 and aa 20-25
Immunogen: Recombinant human p53 protein
Molecular Weight: 53kDa
Positive Control: MDA-231, SKBR-3 cells or Colon CA
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native and denatured)
|Ab without BSA/Azide (Frozen)|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|DO-7 + BP53-12|
|Recombinant human p53 protein|
|Cancer and Tumor Biology|
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