PAAF1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA524984
This antibody is predicted to react with bovine based on sequence homology.PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
|PBS with 0.09% sodium azide|
|PAAF, Rpn14, WDR71, WD repeat domain 71, WD repeat-containing protein 71|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1|
|Antigen affinity chromatography|
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