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PACSIN2 Rabbit anti-Human, Mouse, Non-human primate, Rat, Xenopus laevis, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141564

Catalog No. 01-675-183


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Description

Description

This antibody is predicted to react with mouse, rat, canine, bovine, and chicken based on sequence homology.

PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
Specifications

Specifications

PACSIN2
Polyclonal
Unconjugated
PACSIN2
Liquid
PACSIN2, pacsin2.S
Synthetic peptide corresponding to residues 400-450 of human PACSIN 2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate, Rat, Xenopus laevis
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.2% gelatin and 0.05% sodium azide
Q9UNF0, Q9WVE8, Q9QY17, Q9DDA9
RP3-437M21.1, SDPII
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
11252, 124461, 23970, 398138
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