PACSIN2 Rabbit anti-Human, Mouse, Non-human primate, Rat, Xenopus laevis, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141564
This antibody is predicted to react with mouse, rat, canine, bovine, and chicken based on sequence homology.PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
|Synthetic peptide corresponding to residues 400-450 of human PACSIN 2.|
|Antigen affinity chromatography|
|Human, Mouse, Non-human primate, Rat, Xenopus laevis|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.2% gelatin and 0.05% sodium azide|
|Q9UNF0, Q9WVE8, Q9QY17, Q9DDA9|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|11252, 124461, 23970, 398138|
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