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GPR37 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513412

Catalog No. PIPA513412


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Description

Description

Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.
Specifications

Specifications

GPR37
Polyclonal
Unconjugated
GPR37
Liquid
GPR37
KLH conjugated synthetic peptide between 97-126 amino acids from the N-terminal region of human Pael-R (GPR37)
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
2 mg/mL
PBS with 0.09% sodium azide
O15354, Q9QY42
Endothelin B receptor-like protein-1; ETBR-LP-1; Parkin-associated endothelin receptor-like receptor; endothelin receptor type B-like; PAELR; G protein-coupled receptor 37; GPR37
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
14763, 2861
Documents
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