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MilliporeSigma™ anti-Pan-Ras Asp12 (Ab-1), Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ PC10L100UG

Catalog No. PC10L100UG

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.



Specifically detects Pan-Ras Asp12 Clone: in Human, Mouse, Rat samples, and it is validated for Immuno Blotting

The humanras gene family consists of three identified members H-, K- and N-ras encoding proteins of 188-189 amino acids and 21,000 (p21) molecular weight. Human H-and K-ras are the homologues of v-H- and v-K-ras sequences originally isolated from Harvey and Kirsten strains of rat sarcoma viruses. Normal human cellularras genes are referred to as proto-oncogenes, and have the potential for activation to oncogenes by mutations occurring in codons 12, 13 and 61; such mutated, activated and transformingras genes have been identified and isolated from human tumors and cultured tumor cells. Although the expression patterns ofras proto-oncogene proteins in normal human tissues are known, similar information for activatedras oncogene encoded p21's and its relevance to human disease diagnosis and prognosis remains to be determined.


Pan-Ras Asp12
a synthetic peptide (KLVVVGADGVGK) corresponding to amino acids 5-16 of Ras (H, K, or N) with Asp at position 12
2°C to 8°C
Human, Murine, Rat
Immuno Blotting, Immunoblot
Lyophilized from 20mM ammonium bicarbonate, 100μg BSA.
Recognizes the ∽21kDa H-, K-, and N-Ras proteins containing aspartic acid at position 12.
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