pan Synuclein Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA138705
This antibody is predicted to react with rat samples based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is brain tissue.Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. The alpha- and beta-synuclein proteins are found primarily in brain tissue, where they are seen mainly in presynaptic terminals. The gamma-synuclein protein is found primarily in the peripheral nervous system and retina, but its expression in breast tumors makes it a candidate as a marker for tumor progression.
|PBS with 1% BSA and 0.1% sodium azide; pH 7.6|
|O76070, P37840, Q16143|
|PD1, NACP, PARK1, PARK4, SR, BCSG1|
|-20° C, Avoid Freeze/Thaw Cycles|
|6620, 6622, 6623|
|Immunohistochemistry (Paraffin), Western Blot|
|SNCA, SNCB, SNCG|
|Synthetic peptide near N-terminus of human alpha, beta, gamma synuclein protein|
|Antigen affinity chromatography|
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