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Pannexin 1 Rabbit anti-Mouse, Rat, Polyclonal, Invitrogen™ Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only.

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen 488000

Catalog No. 48-800-0


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Description

Description

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

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Specifications

Specifications

Pannexin 1
Polyclonal
Unconjugated
Panx1
Liquid
Panx1
Synthetic peptide derived from the internal region of the mouse Pannexin 1 protein (AccessionNo. NP_062355), which is identical to rat and human sequence.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Mouse, Rat
Immunohistochemistry, Western Blot
0.25 mg/mL
PBS with 0.1% sodium azide; pH 7.4
Q9JIP4, P60570
PANX1, Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028
Rabbit
IgG
100 μg
-20°C
Primary
315435, 55991
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