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PAR4 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA138505

Catalog No. 01-673-878


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Description

Description

This antibody is predicted to react with mouse and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is heart tissue.

Prostate apoptosis response-4 (Par-4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain-containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par-4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration.
Specifications

Specifications

PAR4
Polyclonal
PBS with 1% BSA and <0.1% sodium azide; pH 7.6
Q96IZ0
PAR4, Par-4, PRKC apoptosis WT1 regulator protein, WT1-interacting protein, prostate apoptosis response 4 protein, prostate apoptosis response protein 4, prostate apoptosis response protein PAR-4, transcriptional repressor PAR4
Rabbit
IgG
1 mL
4° C, do not freeze
Primary
5074
Immunohistochemistry (Paraffin)
Unconjugated
PAWR
Liquid
PAWR
Synthetic peptide derived from C-terminus of human prostate apoptosis response 4 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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