Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

PAR4 Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1755

Catalog No. PA1755

Add to cart



PA1-755 detects prostate apoptosis response protein (Par-4) from human and rat tissues. PA1-755 has been sucessfully used in Western blot procedures. By Western blot, this antibody detects an ~40 kDa protein representing Par-4 in AT-3 cell extract. In Western blots of rat tissue extracts, including testes, spleen, ovary, lung, and skeletal muscle, ~40 kDa and ~38 kDa proteins representing Par-4 are detected. In Western blots of T47D cell extracts, an ~40 kDa protein representing Par-4 and a smaller ~20 kDa unknown protein is detected. PA1-755 immunizing peptide corresponds to amino acids residues 324-342 from human Par-4. PA1-755 immunizing peptide (Cat. No. PEP-060) is available for use in neutralization and control experiments.

Prostate apoptosis response protein (Par-4) is an ~38 kDa protein containing a leucine zipper at its carboxy terminus. The leucine zipper is required for Par-4 function during apoptosis and has also been shown to directly interact with Wilm’s Tumor Suppressor, WT-1. Par-4 is up-regulated in apoptotic prostate cells and has also been observed at ~18 times higher concentration in human brain tissue from Alzheimer ft.s patients when compared to unaffected brain tissue.


Synthetic Peptide: C E(324) Q L K Q E N K T L L K V V G Q L T R(342)
Antigen affinity chromatography
Human, Rat
Western Blot
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
Q96IZ0, Q62627
Prostate Apoptosis Response-4, PRKC apoptosis WT1 regulator protein, PAWR
200 μg
-20° C, Avoid Freeze/Thaw Cycles
5074, 64513
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit