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PTH1R Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA120597

Catalog No. PIPA120597


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Description

Description

PA1-20597 detects Parathyroid Hormone Rec. 1 in human samples. PA1-20597 has been successfully used in immunohistochemistry (paraffin) procedures. The PA1-20597 immunogen is a synthetic peptide, corresponding to the N-terminal extracellular domain of human Parathyroid Hormone Rec. 1.

Parathyroid hormone receptor 1 is a member of the G-protein coupled receptor family. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen ft.s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Parathyroid hormone receptor 1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus.
Specifications

Specifications

PTH1R
Polyclonal
Unconjugated
PTH1R
Liquid
PTH1R
Synthetic peptide, corresponding to the N-terminal extracellular domain of human Parathyroid Hormone Rec. 1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 0.01% sodium azide; pH 7.7
Q03431
PTHR1, Parathyrin, PTH, Parathormone,
Rabbit
IgG
25 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5745
Documents
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