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DJ-1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA137560

Catalog No. 01-673-367


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Description

Description

This antibody is predicted to react with bovine, chicken, canine, mouse, porcine and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is normal breast tissue.

DJ-1 protein has 189 amino acids and was cloned from a HeLa cell cDNA library as a novel oncogene which weakly transformed NIH3T3 cells. The expression of DJ-1 is induced by growth signals and is translocated from the cytoplasm to the nucleus during the S phase, although no nuclear localization signals are present. It has been suggested that DJ-1 is a mitogen-dependent oncogene product involved in Ras-related signal transduction pathway.
Specifications

Specifications

DJ-1
Polyclonal
PBS with 1% BSA and <0.1% sodium azide; pH 7.6
Q99497
DJ-1, DJ1, Parkinson disease autosomal recessive, early onset 7, oncogene DJ1, protein DJ-1
Rabbit
IgG
1 mL
4° C, do not freeze
Primary
11315
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PARK7
Liquid
PARK7
Synthetic peptide derived from C-terminus of human DJ-1 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
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