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PARP Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA138414

Catalog No. 01-673-826


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Description

Description

This antibody is predicted to react with bovine, chicken, amphibian, mouse and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is tonsil tissue.

PARP uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death and is mediated by the caspase CPP32 protein.
Specifications

Specifications

PARP
Polyclonal
PBS with 1% BSA and <0.1% sodium azide; pH 7.6
P09874
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1, ADP-ribosyltransferase NAD+, poly ADP-ribose polymerase, ADP-ribosyltransferase NAD+, ADP-ribosyltransferase diphtheria toxin-like 1, NAD+ ADP-ribosyltransferase 1, poly ADP-ribose polymerase family, member 1, poly [ADP-ribose] polymerase 1, polyADP-
Rabbit
IgG
1 mL
4° C, do not freeze
Primary
142
Immunohistochemistry (Paraffin)
Unconjugated
PARP1
Liquid
PARP1
Synthetic peptide derived from the N-terminus of human PARP protein
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
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