PARP1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PARP1.

Supplier:  Abnova Corporation PAB11729

Catalog No. 89-115-335

Description

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq

Specifications

• Antigen: PARP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
• Gene: PARP1
• Gene Symbols: PARP1
• Immunogen: A synthetic peptide corresponding to N-terminus of human PARP1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Concentration: Lot specific
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PARP1.
• Formulation: In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
• Gene Alias: ADPRT/ADPRT1/PARP/PARP-1/PPOL/pADPRT-1
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 142
• Content And Storage: Store at 4°C.

For Research Use Only