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PARP1 Rabbit anti-Human, Polyclonal, Invitrogen

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527219

Catalog No. PIPA527219


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Description

Description

PA5-27219 targets PARP1 in IF and WB applications and shows reactivity with Human samples. The PA5-27219 immunogen is recombit fragment corresponding to a region within amino acids 151 and 415 of Human PARP1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Specifications

Specifications

PARP1
Polyclonal
Unconjugated
PARP1
Liquid
PARP1
Recombit fragment corresponding to a region within amino acids 151 and 415 of Human PARP1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
ChIP assay, Immunocytochemistry, Immunofluorescence, Western Blot
0.3 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
P09874
ADPRT, ADPRT 1, ADPRT1, PARP, PARP-1, PPOL, pADPRT-1, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase), ADP-ribosyltransferase NAD(+), NAD(+) ADP-ribosyltransferase 1, poly (ADP-ribose) polymerase family, member 1, poly [ADP-ribose] polymerase 1, poly(ADP-ribose) polymerase, poly(ADP-ribose) synthetase,
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
142
Documents
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