PARP2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA14280
PA1-4280 detects the PARP-2 protein in human samples. PA1-4280 has been successfully used in Western blot procedures. This antibody detects a ~66 kDa protein representing PARP-2 in 3T3 cell lysate. PA1-4280 immunizing peptide corresponds to amino acid residues 43-59 of the 62 kDa human PARP-2 protein. Store at 4°C for 3 months or at -20°C for longer periods.Poly(ADP-ribose) polymerase 1, (PARP-1) and poly(ADP-ribose) polymerase 2 (PARP-2) catalyze the formation of poly(ADP-ribose) polymers in a DNA-dependent manner. PARP-2 displays automodification properties similar to PARP-1. These act by poly(ADP-ribosylation), which is a post-translational modification of nuclear proteins in response to DNA damage that activates the base excision repair machinery.
|whole serum with 0.02% sodium azide|
|Poly [ADP-ribose] polymerase 2, NAD(+) ADP-ribosyltransferase 2, Poly[ADP-ribose] synthetase 2, pADPRT-2, hPARP-2|
|Synthetic peptide corresponding to residues Q(43) R Q E S K K M P V A G G K A N K(59) of human PARP2.|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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