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Paxillin Mouse, Unlabeled, Clone: 177, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610569

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Catalog No. BDB610569


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Description

Description

Paxillin, a focal adhesion protein, is a substrate for several tyrosine kinases such as src, FAK, and p120BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. This is consisent with the possibility that paxillin is involved in the regulation of cell morphology. Additionally, because of its SH3-binding domain, paxillin associates tightly with FAK and Crk in an extracellular matrix-independent manner. Although paxillin was initially detected in fibroblasts, its phosphorylation may be important during neurite extension during differentiation.

Specifications

Specifications

Paxillin
177
Unconjugated
Affinity Purified
Aqueous buffered solution containing BSA
150μg
Cell Biology
Primary
Bovine, Canine, Chicken, Human, Murine, Rat
Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
SDS
Documents
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