PCDH12 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520703
A suggested positive control is K562 cell lysate. PA5-20703 can be used with blocking peptide PEP-0818.Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.
|A 17 amino acid peptide near the amino terminus of human PCDH12.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|UNQ395/PRO731, VE-cadherin-2, VECAD2; VE-cad-2; VE-cadherin 2; protocadherin-12; vascular cadherin-2; vascular endothelial cadherin 2; vascular endothelial cadherin-2|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|116808, 51294, 53601|
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