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PCDH12 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520703

Catalog No. PIPA520703


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Description

Description

A suggested positive control is K562 cell lysate. PA5-20703 can be used with blocking peptide PEP-0818.

Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.
Specifications

Specifications

PCDH12
Polyclonal
Unconjugated
PCDH12
Liquid
PCDH12
A 17 amino acid peptide near the amino terminus of human PCDH12.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9NPG4, O55134
UNQ395/PRO731, VE-cadherin-2, VECAD2; VE-cad-2; VE-cadherin 2; protocadherin-12; vascular cadherin-2; vascular endothelial cadherin 2; vascular endothelial cadherin-2
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
116808, 51294, 53601
Documents
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