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PDE11A Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA131146

Catalog No. PIPA131146


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Description

Description

PA1-31146 detects PDE11A from human, mouse, rat samples. PA1-31146 has been successfully used in immunoprecipitation, Western blot applications. The PA1-31146 immunogen is: Synthetic peptide (Human) (N terminal).

The 3 ft.,5 ft.-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3 ft.,5 ft.-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5 ft.-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

PDE11A
Polyclonal
Unconjugated
PDE11A
Liquid
PDE11A
Synthetic peptide (Human) (N terminal).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunoprecipitation, Western Blot
0.7-0.75 mg/mL
proprietary buffer with 0.02% thimerosal
Q9HCR9, P0C1Q2, Q8VID6
FLJ23693, MGC133355, MGC133356, PPNAD2
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
140928, 241489, 50940
Documents
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