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PDE1A Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA131124
PA1-31124 detects PDE1A from human, rat, mouse samples. PA1-31124 has been successfully used in immunoprecipitation, Western blot applications. The PA1-31124 immunogen is: Synthetic peptides (conserved sequence near the N-terminal) unique to PDE1A family members.Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).
|Synthetic peptides (conserved sequence near the N-terminal) unique to PDE1A family members.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunoprecipitation, Western Blot|
|Antibody with no preservative|
|HCAM1, HSPDE1A, MGC26303|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|18573, 5136, 81529|
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