PDE3B Mouse anti-Human, Clone: 4A4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA519555
Peptide Sequence: LTPFPGFYPC SEIEDPAEKG DRKLNKGLNR NSLPTPQLRR SSGTSGLLPV EQSSRWDRNN GKRPHQEFGI SSQGCYLNGP FNSNLLTIPK QRSSSVSLTHCyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
|PBS with no preservative; pH 7.4|
|PDE3B (NP_000913, 401 a.a. ∽ 500 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
|ELISA, Western Blot|
|-20° C, Avoid Freeze/Thaw Cycles|
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