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PDE3B Mouse anti-Human, Clone: 4A4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519555

Catalog No. PIMA519555


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Description

Description

Peptide Sequence: LTPFPGFYPC SEIEDPAEKG DRKLNKGLNR NSLPTPQLRR SSGTSGLLPV EQSSRWDRNN GKRPHQEFGI SSQGCYLNGP FNSNLLTIPK QRSSSVSLTH

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
Specifications

Specifications

PDE3B
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q13370
PDE3B
PDE3B (NP_000913, 401 a.a. ∽ 500 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
ELISA, Western Blot
4A4
Unconjugated
PDE3B
Liquid
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5140
Documents
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