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PDE4B Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA131134

Catalog No. PIPA131134


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Description

Description

PA1-31134 detects PDE4B from rat, mouse, human samples. PA1-31134 has been successfully used in immunocytochemistry, immunoprecipitation, Western blot applications. The PA1-31134 immunogen is: Synthetic peptide (N terminal).

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specifications

Specifications

PDE4B
Polyclonal
Unconjugated
PDE4B
Liquid
PDE4B
Synthetic peptide (N terminal).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
0.68 mg/mL
PBS with 20% glycerol and no preservative
Q07343, P14646
RP5-876C12.1, DKFZp686F2182, DPDE4, MGC126529, PDE4B5, PDEIVB
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18578, 24626, 5142
Documents
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