Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MilliporeSigma™ anti-PDGF (Ab-1) (101-116), Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ PC213L100UL

Catalog No. PC213L100UL


Add to cart

Description

Description

Specifically detects PDGF (101-116) Clone: in Human, Rat samples, and it is validated for ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Immuno Blotting

Platelet-Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B. The protein may exist as either a heterodimer AB or as a homodimer AA or BB. PDGF (BB) has been identified as the human homolog of the v-sis oncogene product and as such has been designated c-sis. The v-sis transforming domain is 89 amino acids in length and is identical in sequence to PDGF (BB). Binding of the PDGF molecule to its specific receptor occurs via interaction with a specific domain on the surface of the molecule known as the V4 surface domain. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.
Specifications

Specifications

PDGF (101-116)
Unconjugated
purified
a synthetic peptide (TEVFEISRRLIDRTNA) corresponding amino acids 101-116 of human PDGF B chain
100μL
2°C to 8°C
Polyclonal
Human, Rat
ELISA, Immuno Blotting, Immunoblot, Immunofluorescence, Immunohistochemistry (Paraffin)
In 0.05M sodium phosphate buffer, 0.2% gelatin.
Rabbit
IgG
RUO
Primary
Recognizes the B subunit of PDGF in mesenchymal cells and fetal epithelial tissue.
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only