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PDHA1 Mouse anti-Bovine, C. elegans, Drosophila, Human, Mouse, Rat, Zebrafish, Clone: 8D10E6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen 456600
When performing ICC and IF heat-induced antigen-retrieval improves signal.|When performing Flow Cytometry Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.|Positive Control: WB: Isolated mitochondria from human, bovine, rat and mouse heart. HepG2 (human liver hepatocellular carcinoma cell line) cell lysate. FACS: HeLa (human epithelial cell line from cervix adenocarcinoma) and HL-60 (human promyelocytic leukemia cell line) cells.The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex.
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|HEPES buffered saline with 0.02% sodium azide|
|A7MB35, P08559, P35486, P26284|
|PDHA, PDHCE1A, PHE1A, PDHE1-A type I, pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, pyruvate dehydrogenase complex, E1-alpha polypeptide 1|
|4° C, do not freeze|
|18597, 29554, 407109, 5160|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|Human recombit PDH-E1-alpha|
|Bovine, C. elegans, Drosophila, Human, Mouse, Rat, Zebrafish|
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