PDH Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526657
DescriptionThe pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
|PBS with 0.09% sodium azide|
|PDHA, PDHCE1A, PHE1A, PDHE1-A type I, pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, pyruvate dehydrogenase complex, E1-alpha polypeptide 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|recombit protein of human PDHA1.|
|Antigen affinity chromatography|
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