PDK4 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA522984
The target sequence has 94% sequence homology with rat and 88% sequence homology with mouse. Suggested positive control: antigen standard for PDK4 (transient overexpression lysate), human heart protein lysate.PDK4 is a mitochondrial protein with a histidine kinase domain that is a member of the PDK/BCKDK protein kinase family. This protein is located in the matrix of the mitrochondria and it ft.s expression is regulated by glucocorticoids, retinoic acid and insulin. PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
|Synthetic peptide made to an internal portion of the human protein (within residues 200-250).|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 30% glycerol and 0.1% sodium azide|
|[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial, pyruvate dehydrogenase kinase, isoenzyme 4, pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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