MilliporeSigma anti-PDX1 (rabbit), Polyclonal,
Manufacturer: MilliporeSigma 061379/DEL
Transcription factor PDX1, also known as pancreatic and duodenal homeobox 1, activates expression of the insulin and somatostatin genes. This protein is a key regulator of islet peptide hormone expression and also plays an essential role in pancreatic development. It has been shown to interact with the basic helix-loop-helix domains of TCF3(E47) and NEUROD1 and with HMG-I(Y). This protein also interacts with the methyltransferase SETD7. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Immunogen: GST-tagged recombinant protein corresponding to the N-terminus of mouse PDX1.
Immunohistochemistry, Western Blotting
|GST-tagged recombinant protein corresponding to the N-terminus of mouse PDX1.|
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