Serum Amyloid P Mouse anti-Rat, Clone: 273912, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523975
In Western blots, 100% cross-reactivity with recombit human (rh) Pentraxin 2 and 25% cross-reactivity with recombit mouse (rm) Pentraxin 2 is observed. In direct ELISAs, no cross-reactivity with rhPentraxin 2 or rmPentraxin 2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
|Serum Amyloid P|
|PBS with 5% trehalose and No Preservative|
|PTX2, SAP, 9.5S alpha-1-glycoprotein, pentaxin-related, serum amyloid P-component|
|-20° C, Avoid Freeze/Thaw Cycles|
|Mouse myeloma cell line NS0-derived recombit rat Pentraxin2/SAP Gln21-Ser228 (predicted)|
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