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Peripherin, clone: 7C5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA110034

Catalog No. 01-670-291

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Peripherin is a Class III intermediate filament subunit found in both the peripheral and central nervous systems, though it is concentrated, as its name suggests, in the neurons of peripherial ganglia and their processes. Antibodies to peripherin can be used in identifying, classifying, and studying neurons in these two systems. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease and some neuronally derived tumors. Peripherin is also a major component of the cytoskeleton of PC12 cells, widely used model system for studies of neuronal differentiation. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin-RDS, a photoreceptor protein associated with retinal degeneration and blindness.

Specifications

Specifications

Peripherin
Monoclonal
Unconjugated
PRPH
Supernatant
PRPH
Purified, recombinant rat peripherin, expressed in E. coli.
500μL
Store at 4°C short term. For long term storage, Store at -20°C, avoiding freeze/thaw cycles.
Primary
5630
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
7C5
tissue culture supernatant with no preservative
P41219, P15331, P21807
Prph1, PRPH
Murine
IgG1, κ
RUO
Antibody
Monoclonal
Human, Murine, Rat
Documents
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