Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Peroxiredoxin V Mouse anti-Rat, Unlabeled, Clone: 44, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 612084

Catalog No. BDB612084

Add to cart



Peroxisomes, ubiquitous organelles of eukaryotic cells, are involved in a number of metabolic processes. Their formation involves membrane generation, targeting and insertion of peroxisomal membrane proteins (PMPs) into the membrane, and transport of matrix proteins across the newly formed membrane. Peroxiredoxins are a family of peroxisomal proteins that includes peroxiredoxin I, II, III, IV, and V. These proteins are homologous to thioredoxin peroxidase, and have been implicated in the reduction of H2O2 levels. Peroxiredoxin V (aka AOEB166/PMP20) is a widely expressed peroxisome matrix protein that contains a C-terminal peroxisomal targeting signal 1 that facilitates binding to the PTS1 receptor, PEX5. Peroxiredoxin V is localized to the cytoplasm and peroxisomes, and displays thiol-specific antioxidant activity in vitro . In rat lung, acute inflammation induced by LPS is associated with an increase in Peroxiredoxin V mRNA levels. Other peroxiredoxins have been shown to reduce the amount of H2O2-induced apoptosis when overexpressed. Similarly, overexpression of Peroxiredoxin V inhibits p53-induced apoptosis. Thus, peroxiredoxin V may be an important anti-apoptotic enzyme found in peroxisomes.

Host Species: Mouse
Clone: 44
Isotype: IgG1
Species Reactivity [for Features Main]: Rat
Immunogen: Rat Peroiredoin V aa. 114-213

Western Blotting



Peroxiredoxin V
Western Blot
Affinity Purified
Rat Peroiredoin V aa. 114-213
Cell Biology
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit