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MilliporeSigma™ anti-PGC-1alpha Clone: 1F3.9,

Mouse Monoclonal Antibody

Manufacturer:  MilliporeSigma™ ST1203100UL

Catalog No. ST1203100UL


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Description

Description

Specifically detects PGC-1α Clone: 1F3.9 in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry, Immunoprecipitation

PGC-1α is a co-activator of PPARα, PPARγ, and other transcription factors that regulates the transcriptonal program of adaptive thermogenesis in brown adipose tissue, hepatic/renal gluconeogenesis, and muscle fiber type switching. The full length protein is detected at 113kDa and is induced in BAT by cold exposure, in liver and kidney by fasting, and in skeletal muscle by exercise. Alternative splicing of the full length gene produces a 270 aa N-terminal splice variant that migrates at ~38kDa and is induced by the same physiological signals which induce expression of the full length protein.
Specifications

Specifications

PGC-1α
1F3.9
In 50mM PBS
Murine
IgG
RUO
Primary
Recognizes the ∽113kDa PGC-1α protein in COS cells.
Immunohistochemistry, Immunoprecipitation
Unconjugated
Purified
A recombinant protein consisting of amino acids 1-120 of mouse PGC-1α
100μL
≤ -70°C
Monoclonal
Human, Murine, Rat
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