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PHF7 Mouse anti-Human, Clone: 1E9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA521951

Catalog No. PIMA521951



Description

Description

Peptide Sequence: GRDSFEDEGR WCLILCATCG SHGTHRDCSS LRSNSKKWEC EECSPAAATD YIPENSGDIP CCSSTFHPEE HFCRDNTLEE NPGLSWTDWP EPSLLEKPES

Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.
Specifications

Specifications

PHF7
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q9BWX1
HSPC045, HSPC226, NYD-SP6, testis development protein NYD-SP6
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
51533
ELISA, Western Blot
1E9
Unconjugated
PHF7
Liquid
PHF7
PHF7 (NP_057567.3, 258 a.a. ∽ 357 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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