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PHKG2 Mouse anti-Human, Clone: 2B8, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519594

Catalog No. PIMA519594


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Description

Description

Peptide Sequence: MTLDVGPEDE LPDWAAAKEF YQKYDPKDVI GRGVSSVVRR CVHRATGHEF AVKIMEVTAE RLSPEQLEEV REATRRETHI LRQVAGHPHI ITLIDSYESS SFMFLVFDLM RKGELFDYLT EKVALSEKET RSIMRSLLEA VSFLHANNIV HRDLKPENIL LDDNMQIRLS DFGFSCHLEP GEKLRELCGT PGYLAPEILK CSMDETHPGY GKEVDLWACG VILFTLLAGS PPFWHRRQIL MLRMIMEGQY QFSSPEWDDR SSTVKDLISR LLQVDPEARL TAEQALQHPF FERCEGSQPW NLTPRQRFRV AVWTVLAAGR VALSTHRVRP LTKNALLRDP YALRSVRHLI DNCAFRLYGH WVKKGEQQNR AALFQHRPPG PFPIMGPEEE GDSAAITEDE AVLVLG

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Specifications

Specifications

PHKG2
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.4
P15735
GSD9C, PHK-gamma-T, PSK-C3, Phosphorylase kinase, gamma 2 (testis/liver), phosphorylase b kinase gamma catalytic chain, testis/liver isoform, phosphorylase kinase subunit gamma-2, serine/threonine-protein kinase PHKG2
Mouse
IgG2a, lambda
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5261
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
2B8
Unconjugated
PHKG2
Liquid
PHKG2
PHKG2 (AAH02541.1, 1 a.a. ∽ 406 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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