PHLPP2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA525995
DescriptionPHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of ft.Ser-473 ft. of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ft.Ser-473 ft. of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3.
|PBS with 0.09% sodium azide|
|PHLPPL, PH domain leucine-rich repeat-containing protein phosphatase 2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 1295-1323 amino acids from the C-terminal region of human PHLPP2|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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