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PHLPP2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525995

Catalog No. PIPA525995

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

PHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of  ft.Ser-473 ft. of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of  ft.Ser-473 ft. of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3.
Specifications

Specifications

PHLPP2
Polyclonal
PBS with 0.09% sodium azide
Q6ZVD8
PHLPPL, PH domain leucine-rich repeat-containing protein phosphatase 2
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
23035
Flow Cytometry, Immunohistochemistry, Western Blot
Unconjugated
PHLPP2
Liquid
PHLPP2
KLH conjugated synthetic peptide between 1295-1323 amino acids from the C-terminal region of human PHLPP2
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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