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Phospho-4EBP1 (Ser65) Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA517906

Catalog No. PIPA517906


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Description

Description

It is not recommended to aliquot this antibody.

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 ft. end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Specifications

Specifications

Phospho-4EBP1 (Ser65)
Polyclonal
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Q13541, Q60876, Q62622
eIF4E-binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; phosphorylated heat- and acid-stable protein regulated by insulin 1
Rabbit
IgG
100 μL
-20°C
Primary
116636, 13685, 1978
Immunoprecipitation, Western Blot
Unconjugated
EIF4EBP1
Liquid
EIF4EBP1
Synthetic phosphopeptide corresponding to the sequence of mouse 4E-BP1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate, Rat
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