Phospho-4EBP1 (Ser65) Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA517906
It is not recommended to aliquot this antibody.This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 ft. end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
|0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5|
|Q13541, Q60876, Q62622|
|eIF4E-binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; phosphorylated heat- and acid-stable protein regulated by insulin 1|
|116636, 13685, 1978|
|Immunoprecipitation, Western Blot|
|Synthetic phosphopeptide corresponding to the sequence of mouse 4E-BP1|
|Antigen affinity chromatography|
|Human, Mouse, Non-human primate, Rat|
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