Phospho-Blooms Syndrome (Thr99) Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523026
DescriptionBlooms Syndrome Protein Blm is a member of the RecQ helicase protein family. The protein contains 1417 amino acids; including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. Blooms Syndrome Protein Blm is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. This gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom ft.s syndrome, namely cancer and diabetes.
|Phospho-Blooms Syndrome (Thr99)|
|Synthetic phospho-peptide surrounding the Blooms Syndrome Protein Blm threonine 99 region|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|tris HCl with 0.2M glycine and 0.1% sodium azide; pH 8.5|
|BS, RECQ2, RECQL2, RECQL3, Bloom syndrome protein, DNA helicase, RecQ-like type 2, recQ protein-like 3|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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