Phospho-4EBP1 (Thr36) Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA512847
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.EIF4EBP1 is a member of a family of translation repressor proteins. This protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 ft. end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. It is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
|PBS with 0.09% sodium azide|
|BP-1; 4EBP1; PHAS-I; MGC431|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T36 of human EIF4EBP1|
|Antigen Affinity Chromatography, Protein A|
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