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Phospho-4EBP1 (Thr36) Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA512847

Catalog No. PIPA512847


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Description

Description

This antibody is predicted to react with bovine, mouse and rat based on sequence homology.

EIF4EBP1 is a member of a family of translation repressor proteins. This protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 ft. end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. It is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Specifications

Specifications

Phospho-4EBP1 (Thr36)
Polyclonal
PBS with 0.09% sodium azide
Q13541
BP-1; 4EBP1; PHAS-I; MGC431
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1978
Dot Blot
Unconjugated
EIF4EBP1
Liquid
EIF4EBP1
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T36 of human EIF4EBP1
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Documents
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