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Phospho-GATA4 (Ser105), Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA122003

Catalog No. PA122003

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

GATA 4 is a 46kDa member of the GATA family of zinc finger-containing transcription factors that is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress-induced gene expression in cardiac and smooth muscle cell types. GATA 4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA 4 is phosphorylated in response to agonist stimulation through MEK 1-ERK 1 / 2, and weakly through JNK or p38 MAPKs.

PA1-22003 detects Phospho-GATA4 (pSer105) in Mouse samples. Expected to cross react with chicken, human and rat due to sequence homology (100% identity with immunogen).PA1-22003 has been successfully used in Western Blot procedures, where a band of 46kDa is predicted to be detected. Positive control: Phenylephrine-stimulated rat cardiomyocytes, transfected with mouse GATA4PA1-22003 immunogen corresponds to Synthetic peptide (Human) derived from a region of GATA 4 that contains serine 105.
Specifications

Specifications

Phospho-GATA4 pSer105
Polyclonal
Unconjugated
GATA4
Purified
GATA4
Synthetic peptide (Human) derived from a region of GATA 4 that contains serine 105.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Murine, Rat
Western Blot
0.5mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
P43694, Q08369, P46152
MGC126629
Rabbit
IgG
50μL
Store at -80°C, Avoid Freeze/Thaw Cycles
Primary
2626
Documents
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