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Phospho-HDAC7 (Ser318) Rabbit anti-Bovine, Canine, Equine, Human, Non-human primate, Zebrafish, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523203

Catalog No. PIPA523203


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Description

Description

Histone deacetylase 7 is a thymus-specific, intracellular, transcription factor belonging to the class IIa histone deacetylase family. Reports suggest that dephosphorylation and nuclear localization of HDAC7 is promoted by Myosin phosphatase, thus regulating the repression of Nur77 and inhibition of apoptosis in CD4+CD8+ double-positive thymocytes. HDAC7 plays a specific role in maintaining vascular integrity by repressing the expression of matrix metalloproteinase (MMP) 10. It promotes repression mediated by transcriptional corepressor NCOR2 and is an efficient corepressor of the androgen receptor (AR). It is also responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).
Specifications

Specifications

Phospho-HDAC7 (Ser318)
Polyclonal
Unconjugated
HDAC7
Liquid
HDAC7, hdac7a
Synthetic peptide (313 CLSRTRSEPLP 322) of Phospho-HDAC-7 pSer318 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Canine, Equine, Human, Non-human Primate, Zebrafish
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q8WUI4
HD7A, HDAC7A, HD7, histone deacetylase 7A
Rabbit
IgG
50 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100050617, 486589, 509843, 51564, 798603
Documents
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