anti-phospho-Histone H3 (Ser10), Clone: 3H10, Millipore™ (Upstate™)

Manufacturer: EMD Millipore 05806DEL

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Catalog No. 50-171-840

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    Specifications

    Antigen phospho-Histone H3 (Ser10)
    Conjugate Unlabeled
    Cross Reactivity Human
    Format Semi-purified
    Host Species Mouse
    Immunogen A proprietary immunogen based on a peptide sequence containing phospho-serine corresponding to residue 10 of human histone H3
    Isotype IgG1 κ
    Quantity 100μg
    Regulatory Status RUO
    Research Discipline Epigenetics
    Primary or Secondary Primary
    Monoclonal or Polyclonal Monoclonal

    Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. GenBank Number: NM_003493. MW: 17kDa.

    Flow Cytometry, Immunocytochemistry, Immunofluorescence, Peptide Inhibition Assay, Western Blotting

  • Description & Specifications

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