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Phospho-JNK1 (Thr183) Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA512867

Catalog No. PIPA512867


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Description

Description

This antibody is predicted to react with mouse, rat and Xenopus based on sequence homology.

MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.
Specifications

Specifications

Phospho-JNK1 (Thr183)
Polyclonal
PBS with 0.09% sodium azide
P45983
Mitogen-activated protein kinase 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, JNK-46, Phospho-JNK
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5599
Dot Blot
Unconjugated
MAPK8
Liquid
MAPK8
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T183 of human MAPK8
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
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