Phospho-JNK1 (Thr183) Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA512867
This antibody is predicted to react with mouse, rat and Xenopus based on sequence homology.MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.
|PBS with 0.09% sodium azide|
|Mitogen-activated protein kinase 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, JNK-46, Phospho-JNK|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T183 of human MAPK8|
|Antigen Affinity Chromatography, Protein A|
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