Phospho-MEK5 (Ser311, Thr315) Rabbit anti-Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen 480024
DescriptionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms. The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
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|Phospho-MEK5 (Ser311, Thr315)|
|0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5|
|HsT17454, MAPKK5, MEK5, PRKMK5, MAP kinase kinase 5, MAP kinase kinase MEK5b, MAPK/ERK kinase 5, MAPKK 5, MEK 5, dual specificity mitogen-activated protein kinase kinase 5|
|Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser311, Thr315 of MEK.|
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