anti-Phospho-p53 pSer15 Clone: 14H61L24, Invitrogen™
Phospho-p53 pSer15 Monoclonal antibody 700439 from Thermo Scientific™ Pierce™ specifically detects Phospho-p53 pSer15 in Human samples, and it is validated for IF, ICC, FACS, ChIP and FRET
Manufacturer: Invitrogen 700439
The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 acetylation at Lys382 is required for recruitment of p300 to the p21 promoter, and is mediated by p300 and CBP acetyltransferases. Acetylation appears to play a positive role in the accumulation of p53 protein in stress responses, and inhibition of deacetylation stabilizes p53.
700439 detects Phospho-p53 pSer15 in Human samples. 700439 has been successfully used in IF, ICC, FACS, ChIP and FRET procedures. The immunogen for 700439 is a peptide corresponding to amino acids 9-19 of P04637.
Chromatin Immunoprecipitation, FACS, Immunocytochemistry, Immunofluorescence
|Store at 2 to 8°C for up to 1 month. For long term storage, store at -20°C.|
|100μg of Protein A antibody in PBS with 0.09% sodium azide;|
|A peptide corresponding to amino acids 9-19 of P04637.|
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok