Phospho-PDGFRB (Tyr1021) Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific LFPA0094

Catalog No. PILFPA0094

Description

A suggested positive control for this product is NIH-3T3 cell treated with PDGF-BB.

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Specifications

• Antigen: Phospho-PDGFRB (Tyr1021)
• Classification: Polyclonal
• Gene: PDGFRB
• Gene Alias: CD140B, JTK12, PDGFR, PDGFR1
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 18596, 5159
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: P09619, P05622
• Gene Symbols: PDGFRB
• Immunogen: Synthetic peptide
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG