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Phospho-PKC mu (Ser742) Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen 44961G

Catalog No. 44-961-G


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Description

Description

PKC mu (protein kinase C mu, PRKD1) is a serine/threonine kinase whose activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway. In addition to the two activation loop sites, the carboxy-terminal Ser916 has been identified as an autophosphorylation site for PKD/PKCu. Phosphorylation at Ser916 correlates with PKD/PKCu catalytic activity. PKC mu is one of the PKC family members, and the protein binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface. Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways.
Specifications

Specifications

Phospho-PKC mu (Ser742)
Polyclonal
Dulbecco′s PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide; pH 7.3
Q15139, Q62101
nPKC-D1, nPKC-mu, protein kinase C mu type, protein kinase C, mu, protein kinase D, serine/threonine-protein kinase D1
Rabbit
IgG
100 μL
-20°C
Primary
18760, 5587
Western Blot
Unconjugated
PRKD1
Liquid
PRKD1
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKCm/PKD that contains serine 742. The sequence is conserved in mouse.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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