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Phospho-PLK1 (Thr210) Rabbit anti-Human, Rat, Polyclonal, Invitrogen™ Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only.

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen 480028

Catalog No. 48-002-8


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Description

Description

Considerable evidence indicates that a Polo-Like Kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.

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Specifications

Specifications

Phospho-PLK1 (Thr210)
Polyclonal
PBS with 50% glycerol and no preservative
P53350, Q62673
Serine/threonine-protein kinase PLK1, Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13, PLK1, PLK
Rabbit
IgG
100 μL
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Primary
25515, 5347
Western Blot
Unconjugated
PLK1
Liquid
PLK1
Immunogen is surrounding Tyr210 of PLK1
Affinity chromatography
RUO
Antibody
Polyclonal
Human, Rat
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