Phospho-PLK1 (Thr210) Rabbit anti-Human, Rat, Polyclonal, Invitrogen™  

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen 480028

Catalog No. 48-002-8

Description

Considerable evidence indicates that a Polo-Like Kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.

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Specifications

• Antigen: Phospho-PLK1 (Thr210)
• Classification: Polyclonal
• Formulation: PBS with 50% glycerol and no preservative
• Gene Accession No.: P53350, Q62673
• Gene Alias: Serine/threonine-protein kinase PLK1, Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13, PLK1, PLK
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 25515, 5347

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: PLK1
• Format: Liquid
• Gene Symbols: PLK1
• Immunogen: Immunogen is surrounding Tyr210 of PLK1
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human, Rat