Phospho-PYK2 (Tyr579), Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA126673

Catalog No. PIPA126673

Description

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined.

PA1-26673 detects PYK2 (phospho Y579) from human samples. PA1-26673 is expected to cross react with mouse (100% conserved) and rat (100% conserved) due to sequence homology.PA1-26673 has been successfully used in Western blot procedures.The PA1-26673 immunogen is a synthetic phosphopeptide corresponding to a portion of human Pyk 2 containing tyrosine 579. The sequence is conserved in mouse and rat.

Specifications

• Antigen: Phospho-PYK2 pTyr579
• Classification: Polyclonal
• Gene: PTK2B
• Gene Alias: FADK, FAK, FAK1, FRNK, pp125FAK
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2185
• Content And Storage: Store at -20°C, Avoid Freeze/Thaw Cycles
• Form: Purified

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q14289, Q9QVP9, P70600
• Gene Symbols: PTK2B
• Immunogen: Synthetic phosphopeptide corresponding to a portion of human Pyk 2 containing tyrosine 579. The sequence is conserved in mouse and rat.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG