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Phospho-POLR2A (Ser5), clone: 8A7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA15875

Catalog No. 01-674-953

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

MA1-5875 detects Phospho-RNA polymerase II CTD in human and S. cerevisiae samples.MA1-5875 has been successfully used in Western blot, ELISA and immunofluorescence procedures.The MA1-5875 immunogen is synthetic peptide, YSPTSpPS (human).
Specifications

Specifications

Phospho-POLR2A (Ser5)
Monoclonal
0.95mg/mL
PBS with 0.1% sodium azide
P24928
RNA Pol2
Murine
IgM
50μL
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Primary
5430, 855459
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
8A7
Unconjugated
POLR2A
Liquid
POL2, POLR2A
Synthetic peptide: YSPTSpPS (Human) from Sp2/0 Ag.14 cells
Protein A
RUO
Antibody
Monoclonal
Human, Yeast
Documents
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