Phospho-RSK1 (Ser380), Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA124771

Catalog No. PIPA124771

Description

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

PA1-24771 detects RSK1 p90 (phospho S380) from human and mouse samples. PA1-24771 is expected to cross react with rat (100% conserved) due to sequence homology. Cross reactivity with RSK2 is expected (85% conserved) based on peptide competition.PA1-24771 has been successfully used in Western blot procedures.The PA1-24771 immunogen is a synthetic phosphopeptide corresponding to a portion of human RSK1 containing serine 380.

Specifications

• Antigen: Phospho-RSK1 p90 pSer380
• Classification: Polyclonal
• Gene: RPS6KA1
• Gene Alias: RP11-492M19.2, HU-1, MAPKAPK1A, RSK, RSK1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6195
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Purified

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q15418, P18653, Q63531
• Gene Symbols: RPS6KA1
• Immunogen: Synthetic phosphopeptide corresponding to a portion of human RSK1 containing serine 380.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG