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Phospho-Synapsin 1 (Ser603) Rabbit anti-Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14604

Catalog No. PA14604


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Description

Description

This antibody is predicted to react with human, Xenopus, bovine, mouse and zebrafish based on 100% sequence homology. In Western blot, this antibody detects an ~78 kDa protein representing Phospho-Ser603 Synapsin I protein.

SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications

Specifications

Phospho-Synapsin 1 (Ser603)
Polyclonal
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
P09951
Brain protein 4.1
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
24949
Western Blot
Unconjugated
Syn1
Liquid
SYN1
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser603 of rat SYN1 conjugated to KLH
Affinity chromatography
RUO
Antibody
Polyclonal
Rat
Documents
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