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Phospho-TERT (Tyr707) Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513048

Catalog No. PIPA513048


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Description

Description

Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.
Specifications

Specifications

Phospho-TERT (Tyr707)
Polyclonal
PBS with 0.09% sodium azide
O14746
Telomerase reverse transcriptase; Telomerase catalytic subunit; HEST2; Telomerase-associated protein 2; TP2; EST2; TCS1; TRT; hTERT
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7015
Dot Blot, Immunocytochemistry, Immunofluorescence
Unconjugated
TERT
Liquid
TERT
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y707 of human TERT
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Documents
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